Platelet-rich plasma or PRP is becoming more popular as a potential treatment for various musculoskeletal conditions. So, what is PRP? Platelet-rich plasma is ultra-concentrated from whole blood.
Usually, blood consists of a large number of red blood cells, a small number of white blood cells, and an even smaller platelet fraction. Red blood cells contain haemoglobin. They are responsible for transporting oxygen from the lungs to various tissues.
White blood cells are integral participants in the normal immune response. They are responsible for fending off infectious agents such as bacteria and viruses. Platelet-Rich Plasma (PRP) Treatment is very beneficial for arthritis as it shows a positive result to many patients.
Image Source – Google
Platelets have a dual function. They are responsible for the initiation of blood clots and to provide assistance for future healing. Platelets are relatively small but contain alpha granules. Alpha granules are loaded with various growth and healing factors.
Examples are platelet derivative growth factor (PDGF), transformation growth factor (TGF), vascular endothelial growth factor (VEGF), and so on.
These growth factors, when released, rush to the site of injury where they form an initial clot that acts as an infection barrier (hemostatic barrier) and serves as a scaffold for other cells responsible for healing to attach.
By releasing various messengers of protein and growth factors, platelets are able to attract white blood cells, red blood cells, and autologous mesenchyme stem cells.