What Is Formalin Fixed Paraffin Embedded Tissues

The formalin-paraffin fixation network or FFPE is invaluable for therapeutic and research applications. FFPE is a specialized technique for preparing and storing tissue samples used in research, diagnosis, and drug development.

Tissue samples are first preserved through a process known as formalin fixation. This step helps maintain vital structures and proteins in the tissues. You can get more information about the ffpe block storage via https://www.geneticistinc.com/blog/storing-ffpe-blocks

 ffpe block storage

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 FFPE PROCESS

The process starts with a sample that is selected and then cut from a donor or patient. Samples can also be taken from other animals such as snakes, rats, or many others. After excision, the tissue is immersed in 10% neutral buffered formalin for approximately eighteen to twenty-four hours. 

The tissue is then dehydrated using increased ethanol concentration. The tissue is then embedded in paraffin to be converted into FFPE blocks. The method used will depend on the needs of the researcher or doctor who requires the FFPE sample. 

The specifications of how the matter will be cut, the size and purpose of the tissue are important. After completing the procedure, the certified pathologist will assess the quality of the sample.

FFPE samples can be stored in hospitals, biobank banks, and research centers. Storage facilities often maintain records of donor tissue collection, storage procedures, and demographic information. 

Demographic information is an important factor in research and clinical trials. Well-preserved FFPE samples are very valuable and can be stored at room temperature for long periods of time.